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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ca84a09a67b9e4735e54fb7467ed4c0340f209ca7d07767237e0365b49adc7' 
  AND token = '0hOtQ01ONJjFPNg8ylqe+cXH9yl/rxpYKGIoQs6ZR08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}