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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd549e876201d1b606e605bda37c0865a5320dee1e1fd4bac4e2819a0cae647c6' 
  AND token = 'kpu4I0pGGtIYP3pyMjV+cWF/qjYEwiv0DlN0nq/Jh30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}