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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204367f236eecaa8c23cbe77fe3d464a2ad1cdb52d9e19199024a37a2d2508ac' 
  AND token = 'Eze6yRorJsTV3ZCX7WOaRJuceSmfhZXmlm2LT0t4Y3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}