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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39164c9b93c929bcc93d599be3b107bf75fb71b3c9ee4dbad62b645900a98edd' 
  AND token = 'jMsx4kjD2eZWEPtiwVk0c0JaAEELnDMRSEvvDHVZwXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}