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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f78a1570be6e4571b250a185ac3bbbe0f4597b7b972a8d37fa62f34c49d93d' 
  AND token = 'hN0iuGRpSY+0VHsHlNHDAUyN7YvRVPxyzhRpRb05/L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}