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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87ccf8164753e9da99e5b26f6f076d963c4e95bfa0f41dddf82aa1341689e8f5' 
  AND token = 'aFjBnDrwOgD1rV3Ab5wQrOwwRn4z3gl4QmYxOfsjGuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}