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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11da9ceda7aa81a51bcf9d39a1ce3502487c716fde8e430a36226ee6f12f0c1e' 
  AND token = 'uyuhlt/QcVyQS1Nms3MTP4dkFRLRe9TtFeR/T8uoGX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}