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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e607e2b43edc8e03a1736a4cebf972d1dbd633b4d101b70c594c1c8f1bd2fee7' 
  AND token = 'ESBfMNNAP8srQ5ugcL1l+LAg3PHotfiRY+VICwYeEvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}