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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f33306ed6eb2feb4ec0144be96e5c8188fd7d508859cf56737f4832ce033fdd' 
  AND token = 'gRV//+moVHG7Y6+m+5QWo2eqOU0Tl28GdgoRwkkb2Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}