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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '819159d1785a4322454ee086c4e8b90dcbd8cb09b3c736271c854fcbf36d7a2c' 
  AND token = 'VUFLTh4WuubpF4tm0LgetHOR4kxsRAAiZ4SU8lNfBXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}