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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bcfaddc6aa1bf5eabbce6fd6b87436921251eac49385ca1cb162f8c0afc52cd' 
  AND token = 'F3CjUZ7hY4LU/dE/nxQFjkUFsB7TmOiSzs02Mz4eMqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}