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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de06648fa215f9d1f676ef7a7f3ac4e67dab915f4aebaf586474a73eb4de9700' 
  AND token = 'cNCoZMyX0K9P264+nG7fCpuax++1uYhyqeyLOxVtOUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}