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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c2e78568fed4468006d9ed125ad5b2ba1e6e8b57aab727ab6f3f1803f00e53' 
  AND token = 'BfLrfx5v5LRCuaevaSIaf1oElH/q0Ccr1IaCj46l1LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}