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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e2c9d7971cc4e2fa4b3b139de990132790aaa4fabb6d0588c2ccd27595714e' 
  AND token = 'q4zRt0yKsHFE+BU99KUfKsoTlB6SR1oyH7OVMPD7IMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}