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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d0a0f408c662dfe59fe13ffab9f79c1536d4cbc01b0a6186a3a4fc9d1f94e2' 
  AND token = '00CVWZw6MiPz+z17PvbCMz6M1KZYbWb4jQ11duyNlno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}