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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29f9eef63c64dc46537f8542b819d3a94beb81df65c96e470d5ff1d80cb2c8f' 
  AND token = 'zPqguOuULJIoloUBE/WuQ6zI07UUExR2SlmTED8InUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}