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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a966cc984f26fbb155dd655fe7541c94736750ccd555ab2b7b3e867dda824544' 
  AND token = '1No+w7XoZ/PoBrWzT7hJy8nkpN3tcUpAOBY0OPWZ61k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}