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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cc4fd29538d9deed88194f4a2976f322e5a02dedb165300f7a6578a5ff184a' 
  AND token = 'cP6K60veCa+TSHpa0deKiUqXJNOumYpi7K/5HRcLRRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}