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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95454d9a11772ea39780ccc78a4ec0e618378604d0e7ebd8d290fb5c08e0084' 
  AND token = 'txfxDhjpMO1haRoKMEPsC1FAP0Luh3lcumJMNvTZYfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}