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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857b38b872762b13324f5ccf23a63b9d63cdfb20b103d70ea50c17e076dba88c' 
  AND token = 'qfdU/UYzMzcO2cuIKA+CH4wjKtQkweeMhE4+6QCITWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}