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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8869693c89bf01d4f9d995322e4921e6d33cb7a483fb24b3dfac7d9e1c2ded0' 
  AND token = 'hRby6OttPZQ5NJN96tTZKc/bcRIZT2xHdOULiPoR0sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}