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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82685f7d946fc9ad1bb78c157b762d52f35d5d0fc0a523356af22ada000e0219' 
  AND token = 'aP7lyA65m28ppETWzaNEYZFoX5xEokI0ADMeEOPtVLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}