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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7cca7f4fc28ca52e01a9a22fecb92b1810a2a712face3287f93e78551f5d2d8' 
  AND token = 'hfiPO5WiuzNSMZrEnSAceirUJr/MWvcTgcjzQ+gF1yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}