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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22bc0cb9c5e837d99b5fcda508309083b084b16403bdacb63e9aed74a52d6f8' 
  AND token = '/QkAQ8Ritep6OBriFuhqzOhRUWIZe5z9Hfe9U3ieEq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}