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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0c0e03c63a7ff124456d991df4a60010e74b57fa2a723bdd33424b75bc36c6' 
  AND token = 'jQeuBFlR5e+u8N4BS+bWFxdtWcB+I+SkRDxvToBYx3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}