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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0056a0090e8d6e17a86241824dbcd7a996ad4da58228e99d020d46ddf7cf3e9d' 
  AND token = 'DLS9WYeyHfh0j0L/E6yQhJLIt8hXWzw/B4WdWmuvOO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}