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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce777328365020dbf5eb508f5796c9ad4df2a3db2a876212f694776971a6559' 
  AND token = 'AyfTxFhs0za774ot4aSq8RvkWbf6/f0sZz/woYMN0OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}