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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165686589f2d7218ace70aac14c922cd28c6ff02f10b7e469cdb09ecf275ac5e' 
  AND token = 'DYB7mSrZYM/ZOB5+VIr8hwuDHm2lVXJ/WU/oeb+F8d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}