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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4832c2395ea7845dca23f12caaf311a0ed853cf2f809ffecf34f62e168d4b37' 
  AND token = 'kDWetVvx2o3lkbQQFlUR8hsLoF+RcYvOmnpUn/T1/hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}