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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e32f02da784104957d4570794a3212baab3a345b22a57ec884da67632880fe' 
  AND token = 'BEpYK+KBd0de0goBAV3wAdtn6XVBbVaNC7t+Z1WXN4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}