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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4572df4af9ac22fa6a11365c94790f511a412661b604b719176174896317770c' 
  AND token = 'U0phO0z4vkCgvecNG+gyXHFRVRXcdqWuDR3s++NlPWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}