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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14f9e533c7ffa1b725555ba4c1f9b65b2d931f33a88fb51d82bbea67581708c' 
  AND token = '9In57npOdXV/zqa6tAg8Uj53Amx7qYmwVOYNC8fjSmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}