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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37c1858900dec36ad4bc1c7ee40032b28bf96fadc0c600402ff6c0520941aab6' 
  AND token = 'Vm8qTNVSKN6hYzU6OAs6nUxQ9TrJVipBhUgRtxNJClM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}