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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae86425acb659382376fb9b9bbe5e7ee84e52ce5f8ff7edb59ed51d1b0fc1163' 
  AND token = 'qs0BqK4q48VFIOeaoYiI13WD1NnzL30DXgJYFcVyNaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}