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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e57e7e8a2c84527387ac63cf62e6d6b8a6149b5186d9b128cc671c5b659003' 
  AND token = 'u6b5pULbRIloM6TSLOXH030XVXdSW4dJPuKPy9/3vqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}