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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b0b850b5f778286f22cb36f9e0dfe32a4e14c328af9769640277777431c6c4' 
  AND token = 'oxNQe/7gp0h+nPSj9nWDezOwZ0bdN3LaikndcHhdwXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}