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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00104a43b4279255d75d73b5858b2a6dc5ce29ed1530a361b610d0c7dcce3677' 
  AND token = 'y1VOkwbuRR7JCScaPQouJFg/h8rvQkIhKssUfwFpQQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}