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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cce92d35e1fa464fdca030cc714bd7b80fb5d6332e6a19c30b0536374fb57918' 
  AND token = '80zvp3V18Uk+SgRWpLrohpXgyPaMxePEl6dD7vlvUfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}