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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16e2dcbea0665a196f4a08990b3758a170759472c5e3efab0d148e720724b3ad' 
  AND token = 'sO6KIgGnzcmP8IMSCXi0OkXOYh/ezDFpXf5PgAQK9P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}