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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5467458b3a9802deee2a2d5b84a31140dbdeec280dd6b9d05a9e5a0b72daa2d' 
  AND token = 'iDMbTBHz5yTwnhD9C2UY/Vx0Idmq5RFaKrP04cS/UTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}