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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9be9b1522d53699c280d4d5950c40e19b227cba182765ab70428a03371e338' 
  AND token = '/aaI4LOIXZtodZj3UfkEFlRQSxfHlps0GC8l/38Z9wU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}