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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591e764933c274f93373febdaf413c84a9b12ffc5e5b48b7e680ac2548988e66' 
  AND token = 'L0eG3rdHcRv3vVkTyPcAlT8VgYA4aXugXX4Mk4DxoD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}