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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5fdc39c4cb64dd1ffa82fc50f1a9ae44360bf36519b394cbb61a0e49e98601' 
  AND token = '+248lRh/SH0Uafkrj3Zaim011KBATm90ciYkxDIDv6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}