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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277134e80bf0c2de450df5b2ce800f330491268fae39b9a6706dabd372b7d5f1' 
  AND token = 'SP3VwaiIhUnPQRF4xxOdxJcwv/17pJAsm2iJmKzLz4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}