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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e89315ce5dbea510bb81a98df066d643919c4346e1f8d72727ad58f95d61c67' 
  AND token = 'HvX4DOYEjMTyF3t3vF7Y+eKishSeNOKKXn86QzQEKv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}