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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54a9052c5d0595effe8a26ec39eb5ffeca6066cbdd0a83db223349b3c476919' 
  AND token = 'Xqt05iJ+QgkN7JiLv0bhwbUcKM+R6msvxrAf4F9/DLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}