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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8776c1756ce594481e00d6e0d54339d379775e5e21314789e327af197fb598' 
  AND token = 'hzfGatIXAKXqMUsJWY9XKJdiy2KKa+/lwG8d/ocDtzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}