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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd536a1cc8cabf718f794d3e9abbda00c15d6cc02d5f17d9006d709ee50e66c56' 
  AND token = 'b8Wd/k7rc/IPaCjbNxsmDlQODB1u3+NB7QMJqCdeQfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}