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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43812aeaace55ca387d49c07091d2f532eedc8804c4a294d5929ea56efa0369' 
  AND token = '/ln49UtCUTJf8VEA7LXQrGIHkEe2NjXFacVN6kxmhkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}