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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c555d0fd4e016bbcdd1088b7116a3b9f52ca034d8bd70b5170692a2fad16a0' 
  AND token = 'OtOGrkcfLGCJbIELF3J+7YGuy1EdQqQfPDzoIgQAW7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}